汕头大学医学院神经科学中心是国际知名学者Melitta Schachner教授领导下的一个高水平实验室。Melitta Schachner教授是德国科学院院士，现任德国汉堡大学分子神经生物学中心主任，美国Rutgers大学教授，是世界杰出神经生物学家、德国功勋科学家，从事神经科学研究近40年，在Cell，Nature，Science，Nature Neuroscience，NatureGenetics，NatureCellBiology，Brain, Glia, J.Neuroscience等杂志已发表重要论文800余篇，担任数十家学术杂志审稿人。汕头大学医学院神经科学中心得到汕头大学医学院和李嘉诚基金会的大力支持，拥有先进的仪器设备，如凝胶成像系统、全功能连续波长微孔板检测仪、MBF体视细胞学计数系统、实验动物行为学分析系统、双光子激光共聚焦显微镜等，为科研人员提供了一个高水准的实验平台。
本中心致力于神经系统疾病基础研究及临床转化实验研究。主要研究方向有：1. 针灸的分子机制； 2. 应用转基因小鼠对神经系统退行性病变如帕金森疾病，阿尔茨海默病和亨廷顿病进行机制性探索； 3. 应用斑马鱼脊髓损伤模型研究神经再生机制； 4. 利用噬菌体展示技术进行抗体筛选制备、目的分子协同剂和拮抗剂的筛选制备等。
实验室近2年所发文章(部分)：
1. Wang Y1, Schachner M1. The intracellular domain of L1CAM binds to casein kinase 2α and is neuroprotective via inhibition of the tumor suppressors PTEN and p53. J Neurochem. 2015 Jun;133(6):828-43. doi: 10.1111/jnc.13083. Epub 2015 Mar 25.
2. Lutz D1, Kataria H1, Kleene R1, Loers G1, Chaudhary H1, Guseva D1,2, Wu B1, Jakovcevski I1, Schachner M3,4. Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Improves Regeneration After Injury. Mol Neurobiol. 2015 Jun 17.
3. Papastefanaki F1, Jakovcevski I2, Poulia N1, Djogo N3, Schulz F4, Martinovic T5, Ciric D5, Loers G3, Vossmeyer T4, Weller H6, Schachner M7, Matsas R1. Intraspinal Delivery of Polyethylene Glycol-coated Gold Nanoparticles Promotes Functional Recovery After Spinal Cord Injury. Mol Ther. 2015 Jun;23(6):993-1002. doi: 10.1038/mt.2015.50. Epub 2015 Mar 25
4.Tang DY1,Yu Y1,Zhao XJ1,Schachner M2,Zhao WJ3. Single chain fragment variable antibodies developed by using as target the 3rd fibronectin type III homologous repeat fragment of human neural cell adhesion molecule L1 promote cell migration and neuritogenesis. Exp Cell Res.2015 Jan 15;330(2):336-45. doi: 10.1016/j.yexcr.2014.10.021
5. Liu D1,Yu Y1,Schachner M2. Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish. Exp Neurol. 2014Nov;261:196-205. doi: 10.1016/j.expneurol.2014.06.006. Epub 2014 Jun 11.
6.Pan HC1,Shen YQ2,Loers G3,Jakovcevski I3,Schachner M4. Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice. Neuroscience. 2014 Sep 26;277:356-66. doi: 10.1016/j.neuroscience.2014.06.069. Epub 2014 Jul 9.
现因工作需要，面向海内外招聘博士后2名。应聘基本条件：1、热爱神经生物学研究工作；2、具有生物医学等相关专业博士学位；博士毕业两年内；针灸专业优先考虑；3、有独立承担课题研究的能力，已有以第一作者发表的SCI论文；4、有丰富的分子生物学、神经生物学、免疫学等实验技能；有斑马鱼操作经验以及神经生物学研究背景者优先考虑。工作职责：1、较大程度上能够独立承担课题研究；2、协助合作教授指导研究生。待遇：凡获得国内外博士学位者(39周岁以下)均可申请。在站2年间，博士后每年薪酬待遇可达18万元-20万元。其中，进站人员将获得学校年薪14万元，业绩突出者，年薪可提高到16万元。通过中期和出站考核的博士后，可申请广东省“扬帆计划”粤东西北地区博士后扶持项目，该项目给予博士后每人每年4万元的生活补贴（资助期不超过2年）。此外，每位博士后还可获得李嘉诚人才基金资助科研启动费4万元。
Postdoctoral research associate position at the Neuroscience Center of Shantou University Medical College
The Center for Neuroscience was established in 2008 with the strong and continuing support by the Li KaShing Foundation. National and provincial grant support allows additional support for internationally cutting edge and vigorous research in basic and applied, translational neurobiology dedicated to neurodegenerative diseases as well as cancer biology to elucidate the functions of cell adhesion molecules in normal physiology and pathology of animal models (mouse and zebrafish).The Center for Neuroscience has developed into an internationally renowned research center (being listed third in China for publication citations in chemistry, molecular biology and life sciences) with modern facilities for research in molecular, cellular and behavioral aspects of neuroscience using mice and zebrafish. Work with transgenic models are ongoing to investigate the mechanisms underlying amelioration of the devastating consequences of acute and chronic spinal cord and brain injury as well as neurodegenerative diseases, such as Parkinson's, Alzheimer's and Huntington's diseases in mice, fish and non-human primates.
The Center for Neuroscience is led by Melitta Schachner, a world renowned neuroscientist being among the most cited neuroscientists worldwide. (Hirsch factor 117 in May 2016 according to ISI)
Job Opportunities
We welcome applications from scientists with experience in the techniques and conceptual approaches from neuroscience, biomedicine (including acupuncture) and related specialities. Candidates must have a PhD degree, a good command of English and should preferably have scientific experimental experience in molecular and cellular biology, neurobiology or immunology. The University will provide very competitive salaries and free housing accommodation.
Contact details
Prof. Melitta Schachner, Center for Neuroscience, Shantou University Medical College, 22 Xinling Road, Shantou, Guangdong 515041, China. Telephone: +86 (0)754 8890 0276, E-mail: Schachner@dls.rutgers.edu. We encourage first interactions for interviews by Skype.
